When Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief's auth ...

After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy We ...

As Mercy West merges with Seattle Grace, battle lines are drawn between the two hospital's residents over the patients. ...

Meredith and Lexi's father, Thatcher, walks into Seattle Grace with a need for a transplant that can not happen from outside his family due to his recent bout with alcoho ...

As hospital personnel jockey for notice to keep from being fired, Izzie returns to surgery early and Bailey's triple aneurysm patient refuses her procedure because of her ...

During days 20 through 40 the staff continues toward acceptance. Meanwhile, Arizona takes a manipulative step to diagnose her pain patient and Hunt's amputee patient sink ...

Covering days one through 13, everyone at Seattle Grace fights to save Izzie and George's lives and then deals with the aftermath. Elsewhere, Hunt treats a double amputat ...

Izzie's memory problems panic Alex, the team takes care of a John Doe who was hit by a bus, Bailey rethinks her pediatrics fellowship, and the hospital endures losses. ...

Izzie is torn over whether to have Derek's proposed brain surgery. A soldier on medical leave asks for a radical operation so he can return to active duty. The Chief trie ...

A car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if ...

Izzie's mother comes to town, a little girl shoots her father triggering a conflict between Meredith and the chief, Thatcher reappears, and Callie gets her first taste of ...

Izzie bites off more than she can chew on her first day of chemotherapy, Mark and Derek are forced to work on the same patient, Meredith's plans for a simple wedding take ...

Derek returns to operate on Izzie, whose friends use their duties as residents to avoid her, especially George who feels betrayed because Izzie never told him about what ...

As Derek continues his hiding in the woods, all hands are on deck in an effort to get him back. Izzie insists that Cristina keep her secret about her cancer, while snicke ...

Derek falls apart after the death of his most recent patient, but Meredith is trying hard not to let him give up; Alex refuses to give up on a patient who had an epilepti ...

A mistake in the clinic mixes Izzie's test results with someone else's and sends her on a mission; a mistake by a general surgeon sends Cristina on a mission of her own; ...

Owen runs into someone very special from his past. Izzie employs her fellow doctors in a medical game made to help teach the interns. Naomi, Sam and Addison rush Archer t ...

Cristina carries on an intense flirtation with Owen, Derek gets advice from everyone on how to propose, Izzie gets some tests done, and Bailey's promotion may stand in th ...

Derek's death row patient attempts suicide and Meredith looks the other way while everybody scrambles for an organ donor. Lexie keeps stumbling into walls after putting M ...

Derek refuses to let a death row inmate die from injuries sustained in a prison riot, Miranda refuses to let a little boy die because he can't get the badly-needed transp ...

Bailey doesn't see eye-to-eye with the new pediatric surgeon on a case she's been involved in for some time. Derek doesn't see eye-to-eye with a patient who's on death ro ...

The race for a resident's first solo surgery comes down to Cristina, who was disqualified because of the actions of her interns, while at the same time is put under press ...

The interns ask for help from Cristina and Meredith when their back room study group has a set back while Izzie continues to wrestle things in her mind by herself. Patien ...

Meredith's best friend from college shows up on her doorstep and Cristina feels threatened by it. Meredith thinks Sloan is putting the moves on her half-sister and asks D ...

The residents compete for the opportunity to be the first one to solo, but Izzie's demons return in the form of a patient of Dr. Hahn's, who finds out the real reason her ...

The new military doctor brings a new training method to the residents and interns for dealing with trauma, while Miranda is presented with the task of treating a ten year ...

George's first day as a resident includes being on a team of surgeons who is performing six kidney transplants in one day, which helps to distract him in seeing that Lexi ...

Callie worries over her first real date with Erica. Cristina stumbles upon a neglected area of the hospital. ...

Determined to reverse Seattle Grace's slide into mediocrity, the chief lays down some new rules for interns and residents with which no one's happy. Derek asks Meredith f ...

As a group of best friends deal with the aftermath of their car crash, Dr. Torres takes the lead on a groundbreaking course of treatment for one of the patients. Meanwhil ...

Meredith and Derek find that happily ever after isn't as easy as they hoped, Cristina finds interest in a military doctor, and the Chief is surprised to hear that Seattle ...

Meredith and Derek are at odds over whether or not to continue with their 13th clinical trial patient and the doctors lift the final critical pieces of cement from the yo ...